Target Name: Phosphatidylinositol 3-kinase complex (PIK3C3, PIK3R4)
NCBI ID: P22484
Review Report on Phosphatidylinositol 3-kinase complex (PIK3C3, PIK3R4) Target / Biomarker Content of Review Report on Phosphatidylinositol 3-kinase complex (PIK3C3, PIK3R4) Target / Biomarker
Phosphatidylinositol 3-kinase complex (PIK3C3, PIK3R4)
Other Name(s): PI3K complex

PI3K Complex as Drug Targets Or Biomarkers

The Phosphatidylinositol 3-kinase (PI3K) complex is a protein cascade that plays a crucial role in cellular signaling. The PIK3C3 and PIK3R4 components of the PI3K complex are key players in this process, and research has identified them as potential drug targets or biomarkers.

The PI3K complex is a transmembrane protein that is involved in various signaling pathways, including cell survival, angiogenesis, and inflammation. The PIK3C3 and PIK3R4 components of the complex are critical for the activity of the PI3K pathway.

The PIK3C3 protein is a 21-kDa protein that is highly expressed in various tissues, including brain, heart, and muscle. It plays a key role in regulating cell signaling, including the PI3K pathway. The PIK3C3 protein has been shown to interact with various signaling molecules, including the transcription factor, NF-kappa-B, and the protein, p16INK4a.

The PIK3R4 protein is a 23-kDa protein that is also highly expressed in various tissues. It interacts with the PIK3C3 protein and is involved in the regulation of cell signaling. The PIK3R4 protein has been shown to interact with various signaling molecules, including the protein, S100, and the transcription factor, NF-kappa-B.

The PI3K pathway is involved in various cellular processes, including cell survival, angiogenesis, and inflammation. The PIK3C3 and PIK3R4 components of the complex are critical for the activity of this pathway. They have been shown to interact with various signaling molecules, including the transcription factor, NF-kappa-B, and the protein, S100.

Research has identified the PIK3C3 and PIK3R4 components of the PI3K complex as potential drug targets or biomarkers. The PIK3C3 protein has been shown to interact with various signaling molecules, including the transcription factor, NF-kappa-B, and the protein, p16INK4a. The PIK3R4 protein has also been shown to interact with various signaling molecules, including the protein, S100.

In conclusion, the Phosphatidylinositol 3-kinase complex (PI3K) is a protein cascade that plays a crucial role in cellular signaling. The PIK3C3 and PIK3R4 components of the PI3K complex are key players in this process. Their research has identified them as potential drug targets or biomarkers, and further studies are needed to understand their role in cellular signaling.

Protein Name: Phosphatidylinositol 3-kinase Complex (PIK3C3, PIK3R4)

The "Phosphatidylinositol 3-kinase complex (PIK3C3, PIK3R4) Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about Phosphatidylinositol 3-kinase complex (PIK3C3, PIK3R4) comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

Phosphatidylinositol 4-Kinase (PI4K) | Phosphatidylinositol 4-Kinase beta (PI4K-beta) | Phosphatidylinositol 4-phosphate 5-kinase | Phosphatidylinositol N-acetylglucosaminyltransferase | Phosphatidylinositol-5-phosphate 4-kinase | PHOSPHO1 | PHOSPHO2 | PHOSPHO2-KLHL23 | Phosphodiesterase | Phosphodiesterase 1 (PDE1) | Phosphodiesterase 6 (PDE6) | Phosphodiesterase 8 (nons | Phosphodiesterase IV (PDE4) | Phosphoglucomutase 5 pseudogene 1 | Phosphoglycerate kinase | Phospholipase A | Phospholipase A2 | Phospholipase A2, Cytosolic | Phospholipase A2, Secretory (sPLA2) | Phospholipase C | Phospholipase D | Phosphorylase kinase | PHOX2A | PHOX2B | PHPT1 | PHRF1 | PHTF1 | PHTF2 | PHYH | PHYHD1 | PHYHIP | PHYHIPL | PHYKPL | PI15 | PI16 | PI3 | PI4K2A | PI4K2B | PI4KA | PI4KAP1 | PI4KAP2 | PI4KB | PIANP | PIAS1 | PIAS2 | PIAS3 | PIAS4 | PIBF1 | PICALM | PICART1 | PICK1 | PICSAR | PID1 | PIDD1 | PIERCE1 | PIERCE2 | PIEZO1 | PIEZO2 | PIF1 | PIFO | PIGA | PIGB | PIGBOS1 | PIGC | PIGF | PIGG | PIGH | PIGK | PIGL | PIGM | PIGN | PIGO | PIGP | PIGQ | PIGR | PIGS | PIGT | PIGU | PIGV | PIGW | PIGX | PIGY | PIGZ | PIH1D1 | PIH1D2 | PIK3AP1 | PIK3C2A | PIK3C2B | PIK3C2G | PIK3C3 | PIK3CA | PIK3CA-DT | PIK3CB | PIK3CD | PIK3CD-AS1 | PIK3CD-AS2 | PIK3CG | PIK3IP1 | PIK3IP1-DT | PIK3R1